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Zerafil Dosing
Response Assessment
Treatment Initiation
Asthma Control Test (ACT)
Zerafil Dosing
Response Assessment
Treatment Initiation
Asthma Control Test (ACT)
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Response Assessment
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Step
1
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2
0%
Has the patient received Zerafil® for 4 to 6 months?
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*Note that the dosage of the patient's other medications should not have been changed during this period.
Yes
No
1. Reduction in annual exacerbations:
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0 exacerbations or reduction ≥ 75%
Reduction of exacerbations 50 - 74%
Reduction of exacerbations < 50%
2. Reduction in daily OCS dose:
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Stopping OCS or reduction ≥ 75%
Reduction of daily dose 50 - 74%
Reduction of daily dose < 50%
3. Improvement in Asthma Control Test (ACT) score:
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Improvement ≥ 3 points and score ≥ 20 or improvement ≥ 6 points
Improvement by 3–5 points and score < 20
No clinically relevant improvement (<3 points)
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